How I Survived Late-Stage Cancer (A Fun Story) · Kurzgesagt – In a Nutshell
讲述一种超级毒药如何从意外发现成为救命良药。适合练习医学类词汇和因果关系表达。
This is not a sad story!
这并不是一个悲伤的故事！
Going through chemotherapy was one of the most interesting experiences of my life and my most vivid memory is very funny.
接受化疗是我人生中最难忘的经历之一，其中有一个非常有趣的回忆。
In 2018 I was being treated for stage 3 B testicular cancer that had metastasized into a few lymph nodes and my lung.
2018年，我接受了针对三期B期睾丸癌的治疗。这种癌症已经转移到了多个淋巴结以及我的肺部。
Very serious business unfortunately.
很遗憾，这是一件非常严肃的事情。
Boys and men, check your testicles tonight.
男孩们和成年男性们，请今晚检查一下自己的睾丸。
One day my doctor was about to punish my body with a fresh dose of Cisplatin.
有一天，我的医生准备给我的身体使用新一剂顺铂（Cisplatin）进行治疗。
A cytotoxic hazardous chemotherapy agent.
这是一种具有细胞毒性的、属于危险级别的化疗药物。
One of the absolutely worst ones.
这绝对是最糟糕的作品之一。
Controlled medical violence.
受控制的医疗暴力”。
The villain and hero of this story.
这个故事中的反派与主角。
My buddy Cisplatin came in a green, opaque two liter bag directly from the fridge.
我的朋友“Cisplatin”被装在一个绿色的、不透明的两升袋子里，直接从冰箱里拿出来的。
The doctor connected the infusion to the central venous access in my chest, a tube that led directly to my heart.
医生将输液设备连接到我胸部的中心静脉导管上——那根导管直接通向我的心脏。
But then…
但是然后……
A short moment of inattention and disaster struck: A single drop of the icy liquid escaped.
仅仅因为片刻的疏忽，灾难就发生了：一滴冰冷的液体从容器中溢了出来。
She panicked for a second, checking frantically if the liquid had landed on her doubly gloved hands or her skin.
有那么一瞬间，她陷入了恐慌，疯狂地检查液体是否溅到了她戴着双层手套的手上，或者是否接触到了她的皮肤。
But luckily it had missed.
不过幸运的是，它没有击中目标。
I had to laugh at the scene.
看到那一幕，我忍不住笑了出来。
My doctor, who I trusted deeply, was terrified of a single drop of Cisplatin.
我非常信任的医生，对顺铂（Cisplatin）这种药物极其恐惧——哪怕只是微量也会让他感到极度不安。
And I was about to have a
而我本来还打算……
whole bag flush directly into my heart so it would spread to every last nook and cranny of my body.
这一整袋“东西”直接被注入我的心脏，然后它会扩散到我身体的每一个角落。
And then again tomorrow.
然后，明天又会再来一次。
Yeah sure, let’s go!
好的，那我们开始吧！
But seriously, how absurd is it that this stuff is medicine?
但说真的，这种东西竟然被当作药物来使用，这到底有多荒谬啊？
So let me tell you the story of a revolutionary chemical that was almost discarded as a failure because it was too brutal,
让我给你们讲一个关于这种革命性化学物质的故事：它差点就被当作失败品被抛弃了，因为它的作用方式实在过于“激烈”（或者说，它的副作用过于严重）。
too toxic, too dangerous.
毒性太强，危险性太大。
A molecule that punched me in the face and wrecked my body.
一种分子——它仿佛一记重拳击中了我的面部，彻底摧毁了我的身体。
And then saved my life and millions more.
然后它救了我的命，也拯救了数以百万计的人的生命。
Cisplatin - The Super Toxic Wonder Drug Cisplatin is a heavy metal compound.
顺铂（Cisplatin）：这种具有超强毒性的“神奇药物”实际上是一种重金属化合物。
A tiny molecule with a platinum atom at its center that looks like a quadcopter.
这是一种非常微小的分子，其中心含有一个铂原子；其结构看起来类似于四旋翼飞行器（即一种具有四个旋翼的飞行器）。
Its success story, like many medical breakthroughs, began with an accident.
它的成功故事，就像许多医学突破一样，始于一次意外。
In the 1960s physicist Barnett Rosenberg wanted to see if he could manipulate living beings with electricity and learn interesting things because why not.
20世纪60年代，物理学家巴尼特·罗森伯格（Barnett Rosenberg）想探究是否可以利用电来影响生物体的行为，并从中发现一些有趣的现象——毕竟，为什么不试试呢？
Well it turns out electricity did nothing but instead he found something huge: The bacteria in a solution with platinum electrodes turned into spaghetti,
结果发现，电力并没有产生任何作用；相反，他发现了一个非常有趣的现象：在含有铂电极的溶液中，细菌竟然变成了类似意大利面条状的物质。
300 times longer – but way more important: They stopped multiplying.
它们的寿命延长了300倍；但更重要的是：它们不再继续繁殖了。
It turned out platinum molecules did that.
原来，是铂金分子起到了这种作用。
At the time chemotherapy was gaining popularity as a treatment for cancer – any chemical that stopped cell division was a potential candidate.
当时，化疗作为一种治疗癌症的方法正逐渐受到重视；任何能够阻止细胞分裂的化学物质都有可能被用作抗癌药物。
Rosenberg felt like he should inject Cisplatin into mice with cancer to see what happened because why not.
罗森伯格觉得应该给患有癌症的小鼠注射顺铂（Cisplatin），看看会发生什么——反正也没什么坏处。
And oh boy, did things happen!
哦，天哪，真是发生了太多事情啊！
While high doses turned out to be deadly to the poor rodents, on lower doses their tumors shrank,
虽然高剂量的药物对这些可怜的啮齿动物具有致命性，但在较低剂量下，它们的肿瘤却缩小了。
did not come back and the mice survived!
那些老鼠再也没有回来，不过它们还是活了下来！
Until they were cut open to make sure of course!
当然，在被切开之前，人们是无法确定情况的。